The University of Washington Department of Laboratory Medicine is seeking research participants
Patient-Driven Clinical Classification of Genetic VUS (Variants of Uncertain Significance)
Have you received a clinical genetic report with a finding of a gene variant of uncertain significance (VUS)?
Are you highly-motivated to learn more about what this genetic variant means for you and your family?
If so, you may be interested in this study.
The purpose of this study is to:
• Help individuals and families understand why VUSs are not medically well understood
• Educate and help individuals and families find more information about the VUSs that are unique to them
• Help individuals identify and collect DNA samples from their family members in order to learn more about their VUS
As part of this study you will use an online resource to learn how to find and contact close and distant family members who may carry your same VUS. You will ask close and distant family members to contribute saliva samples for DNA analysis. There are no costs for the DNA analysis as part of this study.
• You will be asked to contribute a saliva sample for DNA analysis to confirm your VUS report
• If you meet study requirements, you can use an online website to learn how to find and contact distant family members who may also carry the same VUS
• For relatives interested in participating, study staff will arrange sample collection
• Analysis of family information will be done to determine if there is enough information about the VUS in your family to determine if your VUS increases the risk of developing the disease
If interested, please contact Research Coordinator/Genetic Counselor
- Ginger J. Tsai, M.S., C.G.C.
- (617) 733-3930
We look forward to hearing from you!